MFRMs®

Oral neuroprotection for vision, hearing, and cognition

MFRMs are a patented class of orally active small molecules designed to reduce oxidative stress and metal imbalance across the eye, inner ear, and brain.

Overview

At a glance

Oral Molecules

Small molecules designed for systemic neuroprotective activity.

Dual Action

Combines radical scavenging with selective metal binding.

Dual Action

Combines radical scavenging with selective metal binding.

Preclinical Stage

Demonstrated efficacy across multiple neurodegenerative models.

Preclinical Stage

Demonstrated efficacy across multiple neurodegenerative models.

Broad Uses

Relevant to vision, hearing, cognition, aging, and trauma.

Broad Uses

Relevant to vision, hearing, cognition, aging, and trauma.

Science

How it works

MFRMs were designed to go beyond traditional antioxidants by combining free radical neutralization and metal-balancing activity in a single orally active molecule.

Neutralizes damaging free radicals

Selectively binds iron, copper, and zinc

Inhibits ferroptosis cell death

Helps restore redox balance in vulnerable tissues

Penetrates the eye, inner ear, and brain

Avoids key stability limits of many antioxidants

Benefits

What it protects

Vision

Supports retinal, lens, and corneal tissues against oxidative stress and degeneration.

Vision

Supports retinal, lens, and corneal tissues against oxidative stress and degeneration.

Hearing

Helps protect cochlear cells and neural function in noise and blast injury.

Hearing

Helps protect cochlear cells and neural function in noise and blast injury.

Brain

Targets oxidative and metal-linked pathways relevant to neurodegeneration and aging.

Brain

Targets oxidative and metal-linked pathways relevant to neurodegeneration and aging.

Status

A differentiated neuroprotective platform

MFRMs combine broad preclinical activity with a mechanism designed to address multiple drivers of degeneration.

Patented orally active small-molecule platform

Dual antioxidant and metal-binding mechanism

Demonstrated efficacy in vision protection models

Demonstrated efficacy in hearing protection models

Relevant to amyloid beta and neurodegenerative pathways

Potential use across healthy aging, veterinary, and military settings

Want to learn more about our products?

Contact us to learn more about our ophthalmic and neuroprotective product portfolio.

Want to learn more about our products?

Contact us to learn more about our ophthalmic and neuroprotective product portfolio.

Want to learn more about our products?

Contact us to learn more about our ophthalmic and neuroprotective product portfolio.